产品货号:
Z17908
中文名称:
hnRNP-E1/PCBP1抗体
英文名称:
Anti-hnRNP-E1/PCBP1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-hnRNP-E1/PCBP1 Antibody |
指标别名 | Alpha CP1;hnRNP E1;hnRNP X;hnRNP-E1;HNRPE1;HNRPX;PCBP1;poly(rC) binding protein 1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,FCM,ELISA |
基因名称 | PCBP1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human PCBP1 recombinant protein (Position:P152-K268). |
实际分子量 | 40KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Poly(rC)-binding protein 1 is a protein that in humans is encoded by the PCBP1 gene.This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA.This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes.The protein encoded by this gene appears to be multifunctional.It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein.It contains three K-homologous (KH) domains which may be involved in RNA binding.This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure.It has also been implicated in translational control of the 15-lipoxygenase mRNA,human Papillomavirus type 16L2 mRNA,and hepatitis A virus RNA.The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. |
Uniprot ID | Q15365 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | poly(rC) binding protein 1 |
蛋白名全称 | Poly(rC)-binding protein 1 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section IHC 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells ELISA 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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